Great News about Resveratrol

Dr. Jamie McManus

Dear Friends & Family,


The most significant human study to date, which supports the health-enhancing benefits of resveratrol that may address many of the chronic age-related diseases of our time, has just been published!

In a study published this month in Cell Metabolism, Dutch researchers showed that taking a resveratrol supplement for 30 days significantly lowered multiple markers associated with heart disease, diabetes, cancer, and many other chronic diseases. These include markers of inflammation, improved mitochondrial capacity, lowered blood pressure, and blood glucose.

Since inflammation is at the root of literally hundreds of diseases, this has immense potential health implications. And we know that chronic inflammation leads not only to age-related diseases but to accelerated aging, as well! This study also showed reductions in both blood pressure and triglyceride levels, both of which are associated with heart disease risk.

Diabetes has increased a whopping 35% in just the past decade. Until now, the only nonpharmacologic way to improve insulin sensitivity and reduce your risk of developing diabetes has been calorie restriction and weight loss—which is so very hard for people. This study would suggest that adding a high potency resveratrol supplement may help improve your insulin sensitivity and lower blood-sugar levels.

Anyone out there too tired to exercise? Well, this study may provide an answer for this, as well! These study participants showed significant increases in markers of mitochondrial function. Mitochondria are your body’s energy producers that tend to decrease in number and output as we age. The increases seen in this study were similar to those seen with endurance training. So get some of the energy benefits associated with exercise and ramp up your mitochondria just by taking a resveratrol supplement! Sounds too good to be true, but I must say the results here are compelling and exciting.

My advice is that, along with trying to eat better and exercise regularly, it makes better sense than ever to add in a high potency resveratrol supplement to your daily routine.
Learn more about resveratrol products.

 To a longer and healthier life,

Dr. Jamie McManus MD
Chair, Medical Affairs, Health Sciences & Education

Join Shaklee with a $100 order and Get the Gift of Vivix® ~ FREE

Celebrate the Holidays with Our Most Exciting Offer Ever!

Join Shaklee with a $100 order and Get the Gift of Vivix®

When you join Shaklee with an order of $100 or more, we'll give you—FREE—a 30-day supply of Vivix, our all-natural, scientifically advanced supplement developed to Slow Aging at the Cellular Level™*. And it comes in a special holiday-themed box!

A Scientific Breakthrough in Slowing Cellular Aging*

Vivix proprietary ingredients are shown to be 10X more powerful than resveratrol alone in slowing a key mechanism of aging at the cellular level.*
Key ingredients in Vivix have been shown in a clinical study and numerous laboratory studies to improve cell defense, increase cell energy, promote cell repair, and optimize cell performance.*
All natural. Patent pending. Clinically tested key ingredients. Exclusive to Shaklee.

Maximize Your Value with Vitalizer—Include Shaklee Vitalizer™ as a part of your $100 order, and we'll waive the $19.95 membership fee to join!

If you are in Canada, please use this website to join and get your FREE Vivix and FREE membership.

The 700 Club - November 7, 2011 - CBN.com

You can get the Shaklee Vivix Pat recommends at the 56:00 minute right here!

Migraine short story

I apologize that this is so quiet, but if you listen closely, you will hear Mary Ann read a short story of how one person got her life back from migraines, thanks to Shaklee's Vivix.

Do you ever eat Fast Food, Smoke, are Overweight? You might want to read this NEWLY Published Clinical Study!

Letter from Dr. Jamie McManus
New Shaklee Published Clinical Research Study
 
We are pleased to announce the publication of a new Shaklee-sponsored clinical research study confirming that key Vivix® ingredients blunt the biological stress response that occurs after consuming a high-fat meal1.* This biological stress response refers to the acute oxidative and cellular responses that occur in the body to address metabolic by-products of common lifestyle factors such as eating an unhealthful diet, being overweight, or smoking. If the biological stress response persists over time, it may lead to many of the age-related health challenges we see today.


% Change in NRF-2 DNA Binding Activity Following HFHC Meal with or wothout Shaklee SupplementOne way to study this biological stress response is to observe what happens in the bloodstream after eating a high-fat fast food meal, as this is known to produce a significant amount of oxidative and biological stress.

So Shaklee scientists collaborated with researchers to study the effects of Vivix ingredients on the metabolic responses to eating a typical fast food meal. The researchers gave key Vivix ingredients or a placebo immediately before the consumption of a high-fat fast food meal and measured oxidative and biological stress response for five hours following the meal. Results showed significant blunting of the typical oxidative and biological stress response to a high-fat meal, as well as significant activation of Nrf-2, a key regulator of the body’s antioxidant defenses, in the group consuming the Vivix polyphenols.*

The study was published Feb. 2, 2011, online in the Journal of Clinical Endocrinology and Metabolism.Clinicals.Shaklee.com

This research nicely complements our mitochondrial mass study showing increased cellular energy production with Vivix ingredients compared to resveratrol alone AND our laboratory study showing that Vivix ingredients are more powerful than resveratrol at inhibiting AGE protein formation.

What does this mean to you? You can now share the incredible news that we have a human clinical study published in a prestigious peer-reviewed medical research journal that shows significant and positive physiologic effects in people consuming key Vivix ingredients.

To your great health, We encourage you to access the study from your nearest university library or from the Web site and to look for future Health Sciences Bulletins for more information on the health risks associated with oxidative and biological stress responses.
Jamie McManus, MD
Dr. Jamie McManus, M.D.
Chair, Medical Affairs, Health Sciences & Education
Shaklee Corporation
1A Resveratrol and Polyphenol Preparation Suppresses Oxidative and Inflammatory Stress Response to a High-Fat, High-Carbohydrate Meal. Ghanim H, Sia CL, Korzeniewski K, Lohano T, Abuaysheh S, Marumganti A, Chaudhuri A, Dandona P. J Clin Endocrinol Metab. 2011 Feb 2. [Epub ahead of print]

*These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

New Resveratrol + Muscadine Grape Study

A Resveratrol and Polyphenol Preparation Suppresses Oxidative and Inflammatory Stress Response to a High-Fat, High-Carbohydrate Meal

This study showed that a resveratrol and muscadine polyphenol-based supplement suppresses the oxidative and inflammatory stress response to eating a high fat, high carbohydrate fast food meal. The supplement was specifically shown to stimulate the activity of a key regulator of the body's antioxidant defense system,... Nrf-2, and induce the expression of related antioxidant genes. 

See the full study here.